In the past few years there has been a wild search to try and find a brand new drug that will cure and prevent the bird flu and finally the big pharmaceutical companies are linked together in a way that allows them to consistently communicate with each other. These types of computing grids are the speediest and most efficient ways to discover new leads to drug molecules that might help protect against the bird flu.

According to a press realize in the online version of Science Daily there has been collaboration of European and Asian researchers to try and come up with a drug together against the deadly bird flu virus. A new grid computing program has been invented to harness the combined power of more than forty thousand computers ohms research labs across forty five countries to hasten the pace of anti-viral drug discovery.

Called Enabling Grids for E-science, the computing grid strings thousands of ordinary PCs together to form a super-sized supercomputer that is being used during this challenge to analyse the potential of more than 500,000 drug-like molecules. This mass effort is necessary to step up the development of a prescription or even an over counter drug to manage the effects of bird flu in individuals.

This new invention is hot on the heels of new data released last week b they Peking University in Beijing, China. It shows that the H5N1 bird flu virus can pass easily through the placenta of pregnant women to the fetus, and can infect organs other than the lungs in adults. A rapid response to any pandemic outbreak of the virus would be essential to keep a tragedy of unprecedented proportion in check.

New molecules can inhibit the activities of the influenza virus and this computer system helps doctors from across the world find them. Since the grid forts went into effect it is estimated that over 200 molecules have been found that might have the potential to cure the bird flu

There was a bit of hitch in the research and development by Genelabs to develop a new hepatitis drug but according to Chemistry World the day is saved because  Chemistry Lab Genelabs Technologies in a deal worth thirty seven million with GSK.

The development of the world’s first hepatitis E vaccine is currently in Phase II clinical trials and although it is rare in the western world it is endemic in developing countries where it is spread through contaminated water or food at an alarming rate.

All in all there are five different kinds of hepatitis that range from Hepatitis A through to E. Each type differs in how serious is it but there are also many different treatments in development for these problems and almost all of them are by Genelabs. The HCV virus affects about 170 million people worldwide with Hepatitis C being the main offender. Hepatitis C is manageable with a vaccine as well and Genelabs is also in development with many different types of inoculation for that.

The company’s portfolio also included vaccines against hepatitis B and A as well as two antiviral medications for hepatitis B.

The good news about the takeover by GSK is that it will allow research to be continued on all of these drugs by Genelabs Technologies but especially that very rare form of hepatitis called hepatits E. The intention of the drug research for most of these new prescription products is to develop something more effective than the current drugs for hepatitis which are based on a mixture of interferon and ribavarin. The problem with the current standard drugs for this is that they are estimated to be only effective 50% of the time. A drug that works half the time to manage a disease is better than nothing but so much more can be done to improve the quality of life of individuals who have contracted the chronic forms of this disease.

According to an article in the International Herald Tribune the drug Bumetanide has made a big comeback. It is the diuretic that NFL players have been using and it has long been banned from use by professional athletic association.

Athletes have been known to use for rapid loss of pounds so they can look cut and trim on the playing field. Athletes also use it to increase urine production and mask the use of steroids.

This powerful prescription drug works by having the body reabsorb water and sodium from what will eventually become urine. In effect, this potent diuretic exchanging sodium in urine for potassium. The end result from taking the drug is that the user urinates more.

The reason the drug was banned in the first place is because it causes severe dehydration. The athlete also loses potassium, which is key to many body functions — most notably, to keeping the heart beating.

The drug is almost exclusively prescribed to control swelling for patients with heart failure, kidney disease and people with swelling of the limbs, toes and fingers.

The drug has been banned for so long that when news that the drug had once again infiltrated the National Football league they had to call in the experts. Nobody could recall how the drug actually works. It is after all easy to detect and quite dangerous. How is it that drug tests could miss it?

Under the NFL drug policy, players are ultimately accountable for everything that goes in their body. To help them make choices, the league contracts with a not-for-profit company, NSF, that tests supplements. The seal is called the EAS. Currently, EAS products are the only ones certified in the NFL program through NSF

You can get it over the counter in weight building and weight loss supplements but it is not as powerful l as the prescription strength pill and that is what NFL players have been lately accused of abusing.

According to a recent article in Science Daily, a research study published in the FASEB Journal describes how your freckles might be making you fat. Apparently people who have trouble losing weight also make a common antioxidant called melanin in excess. The study was conducted at George Mason University and was a co-research project done in conjunction with INOVA Fairfax Hospital.

Melanin is a very common antioxidant and it helps regulate our skin and eye color. at cells in obese people produce melanin in excess–when they were comparing fat cells of obese people to those of people with normal weight. After the comparison, they found that the gene responsible for making melanin was working in “overdrive” in the fat cells of obese people.

The thing that makes this discovery so exciting is that it makes the invention of a drug that specifically targets fats cells completely possible. In fact some of these drugs already exist and are already FDA approved and available. The fact that they are available is very encouraging should they prove effective for weight loss in the clinical trials that are mandatory to be done before these prescription drugs can be sold and used.

Obesity increases the risk of developing terrible health conditions, such as high blood pressure, stroke, osteoarthritis, dyslipidemia, Type 2 diabetes, heart disease, stroke, gallbladder disease, cancer sleep apnea and respiratory diseases.

No pill can replace diet and exercise but these ones, if approved by the FDA, just might come close. Hopefully this drug will help reduce the enormous cost that obesity causes our culture.